In India the situation is that the graduate courses still needs modification with space of research development in Biochemistry. The author has tried to meet the need in the era of globalization and improvement of market economy. Clinical Biochemistry plays an important role for diagnostic purpose. There was a need for such a textbook to enlighten the current concepts in Biochemistry which has been covered in this book. In the light of recent Medical Council of India recommendations for graduates and post-graduates, this book is far near horizon. Therefore, I feel that present book fills up this gap. I congratulate Dr. Rambabu for covering all topics comprehensively and in simple language