ISBN 9780824701468,Eicosanoids, Aspirin, and Asthma

Eicosanoids, Aspirin, and Asthma



CRC Press

Publication Year 1998

ISBN 9780824701468

ISBN-10 0824701461


Number of Pages 648 Pages
Language (English)

Diseases & disorders

Blending basic science with the latest clinical insights, this important book presents new ideas on the molecular biology, biochemistry, crystallography, and pharmacology of eicosanoids, including their interaction with antiinflammatory drugs and their influence on the mechanisms of asthma.
Surveys a rich panorama of clinical symptoms from the European Network on Aspirin-Induced Asthma, the largest database of its kind in the world!
Edited by clinicians with long experience in the field, Eicosanoids, Aspirin, and Asthma
elucidates basic asthma mechanisms such as genetic influences, viruses, ion airway transport, and autoimmunity
profiles the effectiveness of corticosteroids and aspirin desensitization in asthma treatment
devotes special attention to aspirin-induced asthma
reveals new details on the mechanisms of action of anti-inflammatory drugs
provides evidence for the pneumoprotective action of endogenous nitric oxide
highlights recent applications of crystallography in the understanding of the three-dimensional structure of cyclooxygenase
describes new pathways of arachidonic acid metabolism
explores the clinical manifestations in aspirin-induced asthma
and more!
Complete with over 2000 references, Eicosanoids, Aspirin, and Asthma will be welcomed by pulmonologists and pulmonary physicians, pulmonary rehabilitation therapists, respiratory physiologists, immunologists, allergists, pharmacologists, internists, chest physicians, otolaryngologists, pediatricians, molecular and cell biologists, epidemiologists, neuroanatomists, biochemists, and graduate and medical school students in these disciplines.