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Five-Lipoxygenase Products in Asthma offers an authoritative examination of the biochemistry, basic pharmacology, and clinical pharmacology of the leukotrienes with special emphasis on their role in asthma.
A critical reference for every asthma researcher and clinician, Five-Lipoxygenase Products in Asthma
highlights agents and products of the 5-LO pathway and its relationship to other pathways
explores the enzymology of the 5-LO pathway with focus on leukotriene transport, degradation, and excretion
details the role of protein identification in the 5-LO pathway
describes human cell types that produce leukotrienes and their activation
outlines pharmacological and binding study evidence for leukotriene receptors
discusses the recovery of leukotrienes in lung disease
analyzes leukotriene receptor antagonists and synthesis inhibitors by specific agent
provides a by entity summary of individual drug information in exercise-induced, allergen-induced, aspirin-induced, and chronic stable asthma
profiles the use of agents active on the 5-LO pathway in asthma treatment
With complete discussions of the recovery of leukotrienes in induced and spontaneous asthma and other conditions, Five-Lipoxygenase Products in Asthma, will benefit pulmonologists and pulmonary disease specialists; clinical allergists; internists; chest, intensive care, primary care, and family practice physicians; respiratory therapists; physiologists; pathologists; cell and molecular biologists; and graduate and medical school students in these disciplines.