Lippincott Williams & Wilkins
|Number of Pages
Medicine: general issues
This unique textbook provides an introductory, yet comprehensive overview of the pharmaceutical sciences. It is the first text of its kind to pursue an interdisciplinary approach. Readers are introduced to basic concepts related to the specific disciplines in the pharmaceutical sciences, including pharmacology, pharmaceutics, pharmacokinetics, and medicinal chemistry. In an easy-to-read writing style, the book provides readers with up-to-date information on pharmacogenomics and includes comprehensive coverage of industrial drug development and regulatory approval processes. Each chapter includes critical-thinking exercises, as well as numerous figures, tables, and graphs. Many chapters contain review questions, practice problems, and cases. More than 160 illustrations complement the text.
NEW Case Studies provide students with real-world examples and encourage them to think critically.
Detailed illustrations throughout the book help reinforce key principles.
Emphasis on chemical, biological, and mathematical principles is balanced to help students gain a broad understanding of modern pharmaceutical science and its applications
Review Questions at the end of each chapter help students evaluate their level of comprehension
Key Concepts sections provide a quick review of important material.
Chapter Outlines, tables, and boxes help students master the material.
Additional Reading section points readers to more information.
Table of Contents
Part I: Drug Chemistry
Chapter 1 Introduction
Chapter 2 Drugs and Their Targets
Chapter 3 Ionization of Drugs
Chapter 4 Solubility and Lipophilicity
Part II: Drug Delivery
Chapter 5 Transport Across Biological Barriers
Chapter 6 Drug Absorption
Chapter 7 Drug Delivery Systems
Part III: Drug Disposition
Chapter 8 Drug Distribution
Chapter 9 Drug Excretion
Chapter 10 Drug Metabolism
Chapter 11 Pharmacokinetic Concepts
Part IV: Drug Action
Chapter 12 Ligands and Receptors
Chapter 13 Mechanisms of Drug Action
Chapter 14 Dose-Response Relationships
Part V: Drug Therapy
Chapter 15 Therapeutic Variability
Chapter 16 Drug Interactions
Chapter 17 Pharmacogenomics
Part VI: Special Topics
Chapter 18 Biopharmaceutical Drugs
Chapter 19 Drug Discovery and Approval