Computational modeling is used to make models of the human body and brain for computerized analysis. It is used for various research purposes such as radio-frequency studies, neurology and cancer treatment. Computational modeling also helps in measuring the safety of technology which may use electromagnetic radiation for human usage. The models of the human body and brain are constructed using advanced concepts of mathematics such as non-uniform rational B-spline (NURBS) and polygon meshes. NURBS based computational models are make use of NURBS equations. Polygon mesh-based models comprise a set of vertices, faces and edges which are used to denote the shape of a polyhedral object in 3D space. These techniques allow the simulations to be run in 4-D, where the fourth dimension is time. This book contains some path-breaking studies in the field of computational modeling of the human body and brain. It elucidates new techniques and their applications in a multidisciplinary manner. This book will provide comprehensive knowledge to the readers.