Physical Models of Living Systems is a university textbook that integrates those cutting-edge topics with classic results in statistical inference, control theory, biophysical chemistry and mechanobiology, immunology, and neuroscience, as well as guiding you to create your own stochastic simulations. Instead of offering a huge pile of facts, the discovery-style exposition frequently asks you to reflect on "How could anything like that happen at all?" and then shows how scientists have incrementally peeled back the layers of mystery surrounding these beautiful mechanisms. Working through this book will give you an appreciation for how science has advanced in the past, and the skills and frameworks needed to push forward in the future.