The book deals with the basics of medical imaging informatics in four modules. The first module discusses about information technology and informatics, digital biomedicine/medicine and healthcare information technology. The second module discusses about ontological description in medical imaging informatics, medical image data and workflow in radiology. The third module sheds light on basic medical image processing and analysis, pre-medical image processing and post-medical image processing. The fourth module discusses about medical image displaying, visualization and representation, multi-dimension image representations and multi-scale modelling in medical imaging informatics. Throughout the book, students will find Check Your Progress, i.e., various types of questions. The chapters start with introduction and learning objectives. At the end of each chapter, students will find Summary, Keywords, Exercise, Answers to Check Your Progress and Further Readings. It is an indispensable book to the students of medical science.